6x21- Help Me
Season 6 finale: Cuddy joins House, his team and a search-and-rescue team to assist at the scene of an emergency in Trenton, N.J., where a crane has collapsed onto a building. Among the victims: the guilt-ridden crane operator and a trapped woman (China Jesusita Shavers) who might lose her leg. Meanwhile, House learns that Cuddy and Lucas plan to move in together.

6x20- Bagagge
During a session with Dr. Nolan, House recounts the case of a woman who arrives at the Princeton Plainsboro emergency room with an unexplained illness and no recollection of who she is. While trying to solve the mystery of the woman’s illness, House must also help her piece together her identity.

6x19- The Choice
When a groom collapses at the altar, the team discover that he harbors a secret that will affect their diagnosis. Meanwhile, Wilson pays House's team to take him out, and Taub tries to have an affair despite House's interference.

6x18- Open and Shut
House and the team take on the case of a woman Julia, who is in an open marriage and becomes ill during a date with her on-the-side boyfriend. As perplexing as the case is, Julia’s happy and healthy, yet polygamous relationship is equally baffling to the team. Meanwhile, House tests Wilson’s relationship with Sam.

6x17- Knightfall
House and the team take on the case of Sir William, a “knight” in a closed-off community of men and women living according to the ideals of the High Renaissance. As the team searches the medieval village for environmental factors contributing to Sir William’s rapidly deteriorating health, Thirteen and Sir William debate the acts that define honor and loyalty, especially in regard to the “queen” of the community, one of Sir William’s most frequent visitors. Meanwhile, Wilson starts over with an ex.